Post Doctoral Associate - Surgery

University of Miami

Job Description

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Transforming Lives

The University of Miami is among the top research universities and academic medical centers in the nation, and one of the largest private employers in South Florida.

With more than 16,000 faculty and staff, the University strives for excellence, and is driven by a powerful mission to transform and impact the lives of its students, patients, members of the community, and people across the globe.

The University is committed to fostering a culture of belonging, where everyone feels valued and has the opportunity to add value. Through values of Diversity, Integrity, Responsibility, Excellence, Compassion, Creativity, and Teamwork (DIRECCT) the U community works together to create an environment driven by purpose, excellence, community, and service.

The Department of Surgery has an exciting opportunity for a Full Time Post Doctoral Associate.  The Datta laboratory focuses on understanding how myeloid-derived suppressor cells regulate stromal inflammation and novel mechanism of T-cell dysfunction in pancreatic cancer utilizing in silico , in vitro and in vivo techniques. Moreover, we are a highly translational laboratory, with the express goal of leveraging these preclinical discoveries to develop immunotherapeutic strategies to reprogram the suppressive immune microenvironment in pancreatic cancer.  We are looking for a postdoctoral fellow with a background in tumor immunology and/or cancer biology, with a particular interest in innate immunity, translational immunogenomics, and pancreatic cancer. The candidate will have access to several platforms working with pancreas/GI cancer patient-derived models, including Hyperion imaging cytometry, single-cell RNA sequencing data in human tumors and PBMCs, RNA-seq/whole transcriptome sequencing data from patients’ tumors, and novel in vivo models investigating MDSC biology and its crosstalk with diverse cellular compartments in the pancreatic tumor microenvironment. We have multiple collaborations with pharma companies and are investigating several novel drugs with significant translational promise. Most importantly, our preclinical data translates to clinical trials at Sylvester – the candidate will have a unique opportunity to understand the bench-to-bedside model of cancer research.  The Post Doctoral Associate performs scientific research and studies under the supervision of managing staff. Moreover, the Post Doctoral Associate promotes institutional recognition through literal contributions to the scientific community.


Job Functions

  • Requires the ability to effectively and creatively perform cancer immunology research and take responsibility for assuring quality, cost effectiveness, and timeliness for projects while working under the limited supervision of the PI and/or senior members of the laboratory.

  • Work with animals, as well as animal and human cells/tissues.

  • Maintain mouse colonies

  • Perform immunologic assays (e.g., cytotoxicity assays, myeloid migration studies, immune activity assays, ex vivo co-culture studies, etc.)

  • Perform flow cytometry

  • Perform immunohistochemistry and immunofluorescence.

  • Perform and maintain tissue and cell culture.

  • Develop project proposals in line with research strategy.

  • Rigorously document and maintain a record of research findings.

  • Maintain appropriate databases. Ensure accurate written and computerized records.

  • Effectively communicate and present results.

  • Prepare research results for public presentation through seminars and conferences.

  • Undertakes literature searches for the research project. Interpret and present the findings of the literature searches, advising the research teams appropriately regarding potential projects.

  • Maintain up to date knowledge of subject, experimental, and professional related issues.

  • Ensure all research is undertaken according to good research practice and guidance.

  • Performs other duties as assigned.

  • Conducts research on specific areas of study as assigned.

  • Prepares research reports and technical papers for publishing.
  • Investigates the feasibility of applying a wide variety of scientific principles and theories.
  • Maintains substantial knowledge of state-of-the-art principles and theories.
  • Develops advanced analytical models and systems and provides solutions and analyses to support strategic and tactical decisions.
  • Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.



Ph.D. required.  Master’s or Doctoral degree preferred (in immunology, cancer biology, molecular biology, biochemistry, or genetics, preferred.


Demonstrated track record of productive research experience in oncology or immuno-oncology with at least one peer-reviewed first-author scientific publication, preferred.

Knowledge, Skills and Attitudes:

  • Knowledge of innate and adaptive immune biology, including myeloid cells, neutrophils, macrophages, CD4+ and CD8+ T lymphocytes, is desired.

  • Excellent communication and organizational skills

  • Able to work independently

  • Have strong analytical skills

  • Able to think creatively about experimental design

  • Skill in collecting, organizing, and analyzing data.

  • Ability to recognize, analyze, and solve a variety of problems.

  • Ability to exercise sound judgment in making critical decisions.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University Of Miami Miller School Of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.

Job Status:

Full time

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