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J210501 - Neurobiology - Lubin Lab
University of Alabama at Birmingham in Birmingham, Alabama
 
 
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Date Posted 10/01/2021
Category
Science-Molecular Biology
Employment Type Fulltime
Application Deadline Open until filled
 
 
 
 
 

Epigenetic Mechanisms of Memory in Astrocytes within the Aging Brain

A postdoctoral position is available in an innovative neuro-epigenetics and memory lab to lead a study of transcriptional and epigenetic mechanisms in glia cells initiated by learned experiences that differentially program mature hippocampal neurons in young compared to age. Epigenetic changes in glia cells cause significant disruption of hippocampus-dependent memory processes associated with normal aging and Alzheimer’s Disease.A postdoctoral position is available in an innovative neuro-epigenetics and memory lab to lead a study of transcriptional and epigenetic mechanisms in glia cells initiated by learned experiences that differentially program mature hippocampal neurons in young compared to age. Epigenetic changes in glia cells cause significant disruption of hippocampus-dependent memory processes associated with normal aging and Alzheimer’s Disease.

This NIH-funded project will involve the use of multiple innovative approaches including CRISPR reprograming and next generation sequencing at the single cell level to examine the role of specific non-coding RNAs in astrocytic function and how theses mechanisms relate to age associated memory deficits. Additional methods used in the lab include, survival surgeries, DREADD technology, calcium imaging and behavioral testing. Visit the lab at www.lubinlab.com.

Qualifications:

Highly motivated candidates should have a Ph.D. degree and experience in Molecular Biology. Experience in Bioinformatics, Neuroscience, and molecular genetics is desirable.

Please send a CV, a brief statement of research accomplishments and interests, and a list of references to flubin@uab.edu.

Farah D. Lubin, Ph.D.
Associate Professor
Co-Director, Graduate Neuroscience Roadmap Scholar Program
Co-Director for Research, IRACDA-Mentored Experiences in Research,
Instruction, and Teaching (MERIT) Program
Co-Chair, SoM Black/African American Faculty Association
Department of Neurobiology
University of Alabama at Birmingham (UAB)

About our Postdoc Office:

UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.

About the University:

The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.

Spanning more than 100 city blocks, UAB is the state of Alabama’s largest single employer with some 25,000 employees and has an annual, state-wide economic impact exceeding $7.15 billion. U.S. News & World Report’s 2020 “America’s Best Graduate Schools” ranks 14 UAB graduate programs among the nation’s top 25 and 10 UAB specialties were ranked among the nation’s top 50 in the magazine’s 2018-2019 Best Hospitals report. UAB research grants and awards are at a record high, exceeding $527 million in FY18, including $320 million in NIH funding for FY18. UAB ranks 31st among all universities in federal research funding and 15th among public universities. UAB's NIH funding continues to grow among peer institutions in the Southeast and beyond, with the university ranking 20th among all universities in NIH funding and eighth among public universities. The UAB School of Medicine is ranked 21st among medical schools in NIH funding and eighth among public medical schools.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity, and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.

For more information on Equal Opportunity and Affirmative Action at UAB, visit the UAB Office of Diversity, Equity and Inclusion or call (205) 934-8762. Or contact the office at 701 20th Street South, AB 336, Birmingham, AL 35294-0103.

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