Epigenetic Mechanisms of Memory in Astrocytes within the Aging Brain
A postdoctoral position is available in an innovative neuro-epigenetics and memory lab to lead a study of transcriptional and epigenetic mechanisms in glia cells initiated by learned experiences that differentially program mature hippocampal neurons in young compared to age. Epigenetic changes in glia cells cause significant disruption of hippocampus-dependent memory processes associated with normal aging and Alzheimer’s Disease.A postdoctoral position is available in an innovative neuro-epigenetics and memory lab to lead a study of transcriptional and epigenetic mechanisms in glia cells initiated by learned experiences that differentially program mature hippocampal neurons in young compared to age. Epigenetic changes in glia cells cause significant disruption of hippocampus-dependent memory processes associated with normal aging and Alzheimer’s Disease.
This NIH-funded project will involve the use of multiple innovative approaches including CRISPR reprograming and next generation sequencing at the single cell level to examine the role of specific non-coding RNAs in astrocytic function and how theses mechanisms relate to age associated memory deficits. Additional methods used in the lab include, survival surgeries, DREADD technology, calcium imaging and behavioral testing. Visit the lab at www.lubinlab.com.
Highly motivated candidates should have a Ph.D. degree and experience in Molecular Biology. Experience in Bioinformatics, Neuroscience, and molecular genetics is desirable.
Please send a CV, a brief statement of research accomplishments and interests, and a list of references to firstname.lastname@example.org.
Farah D. Lubin, Ph.D.
Co-Director, Graduate Neuroscience Roadmap Scholar Program
Co-Director for Research, IRACDA-Mentored Experiences in Research,
Instruction, and Teaching (MERIT) Program
Co-Chair, SoM Black/African American Faculty Association
Department of Neurobiology
University of Alabama at Birmingham (UAB)
About our Postdoc Office:
UAB is committed to the development and success of outstanding postdoctoral scientists. Here at UAB, nearly 300 postdoctoral fellows are training currently in a variety of disciplines. Competitive postdoc awards are available including internships, grant incentives, funds to enhance education and collaboration outside UAB, and teaching opportunities at local universities. There is also a Postdoc Research Day with monetary awards. The Office of Postdoctoral Education strongly encourages UAB research mentors to follow the National Research Service Award stipend level guidelines, and postdoctoral scholars qualify for health, life, and other insurances. They also have the right to participate in the university’s 403(b) program and enjoy vacation, sick leave, maternity/paternity leave, and other benefits.
About the University:
The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.
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