POSTDOCTORAL POSITIONS AVAILABLE IN THE GE LAB
Supported by NIGMS MIRA (R35), DoD CDMRP, NIAID R21, and endowment funds
Position Description: Three postdoctoral researcher positions are available from July 2021 in Dr. Xin Ge’s Laboratory at University of Texas Health Science Center at Houston (UTHealth), to study protease inhibitory monoclonal antibodies (mAbs) for therapeutics development (PNAS 2016,113:14970; PNAS 2019,116:16314). The successful candidates will utilize novel protein engineering approaches for the discovery, characterization, and optimization of mAbs specifically inhibiting proteases of medical importance for the treatments of indications such as cancer, obesity, snake envenomation, and diabetic neuropathy.
Qualification and Experience: Applicants should have recently received (or expect soon) a Ph.D. in biochemistry, molecular biology, biochemical engineering or related disciplines. Highly motivated candidates with strong background and experience in protein science and engineering are encouraged to apply. Good publication record and prior experience in protein engineering techniques (e.g. library construction, phage display, FACS) are highly desirable. Qualified individuals should possess the ability to design experiments, interpret and track results, and utilize this information to enable hypothesis generation. Good written and oral communication skills and the ability to work well in a collaborative environment are also required.
Research Environment: Located in the heart of the Texas Medical Center, the Brown Foundation Institute of Molecular Medicine (IMM) is a translational research institute that focuses on studying and preventing diseases at the genetic, cellular and molecular levels. As one of eight research centers within the IMM, the Texas Therapeutics Institute (TTI) particularly encourages drug discovery. The Ge Lab, newly relocated from UC Riverside in summer 2021, aims to develop enabling technologies for facile discovery and engineering of bio-pharmaceuticals, such as inhibitory and neutralizing antibodies and therapeutic enzymes, which are important but challenging for current technologies. The successful candidates will have extensive opportunities for multiple collaborations with scientists at UTHealth and worldwide working in diverse areas of biology and drug discovery.
Application: Please send a single PDF file including a personal statement, a full CV, contact information of references to: Prof. Xin Ge at firstname.lastname@example.org. Applications will be reviewed as they are received. Positions will remain open until filled. For more information on Dr. Ge’s research, please visit: https://gelab.engr.ucr.edu; https://www.ncbi.nlm.nih.gov/sites/myncbi/xin.ge.1/bibliography/public/