Position Title: Postdoctoral Fellow
Purpose: An NIH-funded postdoctoral fellowship in the laboratory of Dr. William Drobyski in the Departments of Medicine and Microbiology at the Medical College of Wisconsin that is focused on transplantation immunology with a specific emphasis on the immunobiology of allogeneic bone marrow transplantation and the pathophysiology of graft versus host disease (GVHD).
Specific areas of interest in include inflammatory cytokine networks that contribute to GVHD, inflammatory cytokine signaling and regulatory pathways that impact the development of tolerance, modulate anti-leukemic responses, and induce pathological damage particularly within the gastrointestinal tract and central nervous system using genetically modified mouse models, flow cytometry, q-PCR, RNA-seq, western blot, single cell RNA seq, and other immunological techniques. Recent publications include Journal of Clinical Investigation 2016; 126: 3541-3555, Blood 2018; 132(4): 435-447, Nature Communications 2018; 9(1): 5037; Blood 2020; 135(8): 568-581 and Blood 2021; 137(9): 1241-1255.
Characteristics of a postdoctoral appointment:
It is expected that postdocs at MCW, with the assistance of their supervisor, will:
- Transition to career independence through the development of professional skills that enable the postdoc to actively pursue a career of his/her own choosing.
- Be supervised by at least one senior scholar who actively promotes the postdoc's professional development.
- Establish an individual development plan (IDP) that incorporates equally the postdoc's career and training goals and the mentor's research goals.
- Pursue basic, clinical, or translational projects so long as effort is focused primarily on research.
- Publish results of the postdoc's research and scholarship during their appointment.
- The postdoctoral appointment is temporary by nature, the aggregate amount of time spent as a postdoc is recommended to not exceed five years (not including family medical leave or maternity/paternity leave).
- As postdocs are important members of the host institution's community, appropriate levels of compensation, health care, and other benefits commensurate with their essential status should be afforded, independent of the postdoc's source of funding.
- Plan, design and execute complex research studies, procedures and protocols pertaining to bone marrow transplantation.
- Participate in discovery projects.
- Coordinate research study activities; lead and manage projects.
- Oversee organization, synthesis and analysis of data and findings.
- Prepare scientific reports, outcome findings and scientific manuscripts.
- Participate in meetings with principle investigator and research staff in which you will evaluate/interpret the validity of data, develop methodologies, and design and evaluate lab procedures.
- Maintain supplies, may require negotiation with vendors, and track purchase orders.
- May oversee the work of laboratory personnel including training and development as well as daily work direction, delegation and establishing priorities.
- Assist in training students and more junior member of the laboratory. Perform other duties as assigned.
Knowledge – Skills – Abilities
Required knowledge: biology, chemistry, mathematics, statistics, documentation, records management, data utilization, complex problem solving, critical thinking, resource management, and writing skills
Skills and abilities:
- Must be adept at designing and performing experiments and interpreting data.
- Excellent communication skills
Building: MACC Fund Research Center, 6061
Division: Hematology and Oncology
Reports to (Title): Principal Investigator – Dr. William Drobyski
Collaborates with (Titles): Research staff and students
Full-time role with expectations for coverage during core business hours and flexibility required as necessary to accommodate business needs.
Minimum Required Education: PhD in Immunology, Microbiology or related field
Minimum Required Experience: No experience required.
Preferred Experience: Immunology, including mouse models, flow cytometry and/or molecular biology. Research skills include immunology, molecular and cellular biology techniques
The Medical College of Wisconsin (MCW) is one of the largest healthcare employers in Wisconsin. We are a distinguished leader and innovator in the education and development of the next generation of physicians, scientists, pharmacists and health professionals; we discover and translate new knowledge in the biomedical and health sciences; we provide cutting-edge, collaborative patient care of the highest quality; and we improve the health of the communities we serve.
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