At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.

Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie

The postdoc in In Vitro Pharmacology/Discovery Biology research will participate in early-stage preclinical human disease model projects at Neurocrine. In collaboration with In Vitro Pharmacology- and Electrophysiology-team members the individual will be a key contributor to the development and implementation of a patient-specific organoid platform.

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• The primary role is to establish a novel human iPSC-derived organoid platform

• Design and perform in vitro studies to support current and future research projects in multiple target/disease areas

• Prepare data summaries and present results to peers and colleagues at Neurocrine

• Present data as appropriate at scientific meetings at the National and International level

• Other tasks as assigned

• Ph.D. in biology, life sciences or related discipline, with experience in the biotech/pharmaceutical industry OR with prior non-industry Ph.D. experience

• Experience in stem cell biology with a focus on differentiation paradigms to derive defined CNS-specific organoid cultures

• Experience with viral and/or non-viral gene delivery, genome-editing (e.g., CRISPR/Cas systems) and delivery of genetic material via diverse delivery methods

• Experience in low to medium electrophysiology methods such as mutli-electrode arrays would be preferred

• Experience with single cell transcriptomic profiling (e.g., 10x Genomics) would be preferred

• General knowledge about the function of the central and autonomic nervous systems

• Experience in advanced experimental technologies and their utilization in the drug discovery process

• Experience with primary and iPSC-derived neural cultures

• Excellent critical analysis skills

• Assimilates data and research findings outside of Neurocrine for application to new scientific projects

• Maintains broad knowledge of scientific principles and theories and possesses intellectual mastery of one or more scientific areas

• Advanced knowledge and demonstrated ability working with / recommending a variety of laboratory equipment/tools

• Ability to work as part of teams

• Excellent computer skills

• Excellent communications, problem-solving, analytical thinking skills

• Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency

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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.

We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.