Research Associate III - CHO Development

Job #24-01A

Mapp Biopharmaceutical, Inc. "Mapp" is a San Diego based, innovative biopharmaceutical company focused on addressing unmet medical needs through the development of life-saving monoclonal antibody treatment options to combat a variety of neglected and tropical infectious diseases, and in support of biodefense programs.

The Early Research and Development Group (ERDG) and the Advanced Research and Development Group (ARDG) at Mapp Biopharmaceutical are responsible for the execution of high quality Research and Development activities to ensure the achievement of a robust portfolio through CMC, Nonclinical, Regulatory, Project Management, and Clinical activities consistent with Mapp's product development objectives.

The Research Associate III - CHO Development position is a technical position within ARDG. The Research Associate III - CHO Development will execute experimental studies, provides some technical direction to junior associates as well as perform general laboratory duties to support Mapp Scientists in meeting their research objectives.

Basic Qualifications

• BA/BS Degree in a related scientific discipline with 4 years relevant research laboratory industry experience OR
• MS Degree in a related scientific discipline with 2 years relevant research laboratory industry experience
• Experience with mammalian cell suspension and tissue cultures
• Experience in generating and screening stable clonal Chinese Hamster Ovary (CHO) cell lines
• Experience with bench-scale bioreactor operation (mammalian culture)
• Experience with protein purification, characterization, and analytical methods
• Familiarity with and use of fully-automated instrumentation (BioHT, Cell Printer, etc.) for the selection of high-producing clones used in antibody discovery and cell line development
• Excellent aseptic/sterile technique
• Conceptual understanding of biological research related activities
• Attention to detail

Preferred Qualifications

• Experience in supervising junior associates and interns
• Experience with pilot-scale (50L to 200L) mammalian cell culture upstream and downstream unit operations
• Experience with mammalian cell culture perfusion bioreactor equipment setup and operation

Responsibilities

• Performs generation, screening, and selection of high producing recombinant clonal CHO cell lines
• Performs early-stage upstream process development of mammalian cultures for production of recombinant therapeutic proteins
• Performs small-scale and pilot-scale bioreactor set-up, operation, and harvest activities
• Prepares media, buffers and solutions to support cell culture and protein analysis assays
• Performs purification and analysis of samples for upstream process development activities, including but not limit to POROS titer assay and spent media amino acid analysis.
• Maintains detailed experimental records
• Generates reports and documents as requested
• Presents effectively and communicates work related results to supervisor and group

Mapp offers a competitive compensation and benefits package in addition to this exciting and challenging job. Mapp's anticipated pay scale for this position is $33.66 per hour - $40.87 per hour plus any applicable bonuses. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the candidate's level of education, and type and length of experience within the job and/or within the industry. Medical, dental, and vision insurance benefits are available to eligible employees and their families. Mapp also provides basic life insurance, short and long term disability, and a 401K plan that includes Company contributions to eligible employees. Full time employees will be provided 7 days of sick time, 14 paid holidays, and will also accrue 18 days of vacation throughout the calendar year.

This position is an on-site position located in Mapp's new state-of-the-art San Diego facility.

Mapp wants you to join their team and invites you to apply by submitting your information through . This job will remain open for twenty (20) days after being posted on Mapp's Job Openings website page (see link).

No Solicitors, agents or placement agencies please. Mapp utilizes E-Verify.

Mapp is an Equal Opportunity/Affirmative Action/Disability/Veterans Employer - Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected Veteran status, or any other characteristic protected by applicable federal, state, or local law.