A postdoctoral research fellowship position under the mentorship of Venkata Lokesh Battula, Ph.D., is available to study Acute Myeloid Leukemia. The laboratory is studying the role of immune checkpoint proteins in AML progression. We are interested in the development of immunotherapy targeting B7-H3 in AML as a part of DoD and LLS funded projects. Postdoctoral fellows are responsible for conducting the in vitro immune cell cytotoxicity assays as well in vivo tumor growth studies. Candidates must have a doctoral degree with 0-2 years of postdoctoral experience. Preference will be given to candidates with previous experience with drug discovery/development, cell-based cytotoxicity assays including flow cytometry, IncuCyte, mouse models, cancer and immune cell biology, basic cell culture, and imaging skills. Candidates are expected to be self-motivated and have excellent writing and communication skills.

LEARNING OBJECTIVES
The potential candidate is expected to quickly learn various tissue culture techniques, immune cell assays, and molecular assays including qRT-PCR, western blotting, ELISA that we routinely use in our laboratory. Also, we have several animal models including patient-derived xenografts that need to be maintained and used for translational research. A thorough understanding of cancer biology, drug development, and immunobiology is appreciated.

ELIGIBILITY REQUIREMENTS
Ph.D. degree in a life science (cellular or molecular biology) within the last three years of matriculation. Research experience and an excellent knowledgebase in biochemical, metabolic, and signaling process as they relate to cancer. Experience in hematologic malignancies, working with suspension and adherent cancer cell lines, the quantitative measurement of mRNA expression, flow cytometry, primary lymphocyte isolation from peripheral blood, big data analysis, and/or the use of animal models would be a plus. The applicant should enjoy providing a training role for students and other coworkers and should be open to scientific collaboration within the institution as well as outside the institution. The candidate should possess excellent written and spoken (English) communication skills and should be able to present scientific data at international meetings.

Candidates should be self-motivated, career oriented, and should be capable of troubleshooting immunology, molecular, cellular, ex vivo, and in vivo studies. Excellent verbal and written communication skills, multiple publications, and strong reference letters are required.

ADDITIONAL APPLICATION INFORMATION
Program dates to be determined. Consideration of applications will begin immediately and will continue until the position is filled. Please review the initial required documents in the SLATE applicant portal and upload as required.

POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:
- Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid Education Vacation and Sick Leave
- Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
- Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illness-related reduced salary pay program
- Health Savings Account and Dependent Care Reimbursement flexible spending accounts
- Fertility benefits
- State of Texas longevity pay
- Extensive wellness, fitness, employee health programs and employee resource groups