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Scripps Staff Scientist - Davis Lab
Job Description
| Classification Title: | Staff Scientist |
|---|---|
| Job Description: | The Davis Lab in the Department of Neuroscience at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology is seeking to hire a Staff Scientist to contribute to our goals of developing novel therapeutics for neurodegenerative diseases. The lab has a large effort that focuses on the impairments in mitochondria in neurons that occur in Alzheimer’s disease, ALS, and other neurodegenerative diseases. We employ multiple techniques in this pursuit, including cell-based assay development; high content screening of small molecules; cell culture of mouse neurons, human neurons derived from iPSCs, and other immortalized cell types; molecular biology and in vivo testing of drugs in both Drosophila and mouse models for neurodegenerative diseases. Successful candidates will perform the vivo testing of drugs in animal models for diseases, perform molecular biological techniques to probe mitochondrial dynamics and function that include Western blotting, Seahorse assays, ATP generation assays, and mitochondrial isolation; and/or behavioral assays of animal models for the diseases such as locomotor activity, measurements of neuromuscular control and strength, and learning and memory. Successful candidates may also participate in screens for potential therapeutics that includes cell culture approaches using mouse neurons or human neurons derived from iPSCs, and high content screening. Details of established essential functions for this position will be addressed/discussed during the interview process. Perform high content/high throughput screens of potential therapeutics using mouse primary neurons Perform mitochondrial functional assays (Seahorse) using iPSC-derived motor neurons from ALS patients Test potential therapeutics in mouse models for ALS Compile and analyze data Present findings at national and local research conferences and lab meetings Assist the PI in writing abstracts and grant proposals Help guide more junior members of the laboratory in concepts and techniques |
| Expected Salary: | Commensurate with experience. |
| Minimum Requirements: | Ph.D. in an appropriate scientific discipline required. A minimum of 2 years postdoctoral experience. |
| Preferred Qualifications: |
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| Special Instructions to Applicants: | In order to be considered, applicants must upload a cover letter and resume. Please provide names and email addresses of three to five references as part of the application process. When ready, the hiring department will contact the listed references via email requesting their reference letters to be uploaded directly to the application website. Applications must be submitted by 11:55 p.m. of the posting end date. This is a time-limited position. |
| Health Assessment Required: | Yes. |
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