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Assistant Project Scientist Position in Pulmonary - Shackelford Lab 2023-2024
Job Description
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Assistant Project Scientist Position in Pulmonary - Shackelford Lab 2023-2024 Apply now to Assistant Project Scientist Position in Pulmonary - Shackelford Lab 2023-2024
Job #JPF08863
- Medicine-Pulmonary Disease / David Geffen School Of Medicin / UCLA
Position overview
Position title: Assistant Project Scientist
Salary range: See Table 37-B [https://www.ucop.edu/academic-personnel-programs/_files/2023-24/july-2023-acad-salary-scales/t37-b.pdf ]. A reasonable estimate for this position is $71,500-$82,900.
Application Window
Open date: September 20, 2023
Next review date: Friday, Oct 20, 2023 at 11:59pm (Pacific Time)
Apply by this date to ensure full consideration by the committee.
Final date: Friday, Oct 20, 2023 at 11:59pm (Pacific Time)
Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
Position description
The Division of Pulmonary and Critical Care, David Geffen School of Medicine at UCLA, has an opening for a full-time Assistant Project Scientist.
The Assistant Project Scientist candidate will perform independent research investigating the molecular and metabolic mechanisms of metabolic adaptation and therapy resistance in non-small cell lung cancer (NSCLC). Their work will focus on 1) characterizing functional and structural mitochondrial phenotypes in NSCLC tumors using super-resolution microscopy, 2) profiling bioenergetics in KRASMUT driven lung tumors using PET imaging radiotracers, 3) performing biomarker validation using both biochemical and immunohistochemical (IHC) techniques and 4) performing pre-clinical trials in KrasMUT genetically engineered mouse models (GEMMs) and patient derived xenografts (PDXs) of NSCLC testing targeted therapies.
Responsibilities:
Develop concepts, identify or generate reagents, perform logical series of experiments to develop understanding of role of LKB1/STK11 in KRAS driving NSCLC, and identify PET probes to guide therapeutic delivery of mitochondrial inhibitors. Additional responsibilities include: genotyping mice, induction of lung tumors in mice, performing micro PET and CT imaging on mice, daily dosing of mice, euthanize moribund mice, harvest of tissue, tissue analysis by biochemical and immunohistological approaches.
Specific Responsibilities:
• Report directly to the Principal Investigator.
• Carry out experiments and analyze the data generated with minimal supervision.
• Supervise undergraduates, graduate students and new postdoctoral trainees in the lab.
• Work on multiple projects efficiently and effectively.
• Assist with preparation of grant proposals.
• Deliver effective presentations and participate actively in weekly laboratory meetings.
• Prepare manuscripts for publication in scientific journals.
• Communicate effectively with other scientists worldwide.
• Maintain and organize the maintenance of critical equipment
• Organize laboratory safety protocols and inventory systems
Required Qualifications:
• Ph.D. in biomedical sciences or related field
• Minimum of 5 years experience in biomedical research with a focus on mouse models of cancer, PET imaging, metabolic flux analysis, biomarker validation and translational research.
Required Skills:
• Experience in molecular and cell biology and 2+ years of specific experience in PET imaging and translational related lung cancer research in experimental animals and cellular systems.
• Experience in recombinant DNA technology, PCR, cell culture techniques, basic biochemistry, immunohistochemistry and mouse models of disease.
• Ability to handle several projects simultaneously.
• Ability to train, advise and supervise laboratory personnel.
• Ability to maintain and supervise the maintenance of high quality scientific records.
The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what’s right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at https://medschool.ucla.edu/cultural-north-star .
Qualifications
Basic qualifications (required at time of application)
A Ph.D. in biomedical sciences or related field is required.
Minimum of 5 years experience in biomedical research with a focus on mouse models of cancer, PET imaging, metabolic flux analysis, biomarker validation and translational research.
Application Requirements
Document requirements
Curriculum Vitae - Your most recently updated C.V.
Cover Letter (Optional)
Statement on Contributions to Equity, Diversity, and Inclusion - An EDI Statement describes a faculty candidate’s past, present, and future (planned) contributions to equity, diversity, and inclusion. To learn more about how UCLA thinks about contributions to equity, diversity, and inclusion, please review our Sample Guidance for Candidates and related EDI Statement FAQ document.
Reference requirements
none
Apply link: https://recruit.apo.ucla.edu/JPF08863Help contact: hdraper@mednet.ucla.edu
Campus Information
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
Job location
Los Angeles, CA
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