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Post-Doc Research Associate

Job Description


Posting Information
Posting Details


Department Pharmacology - 424001
Posting Open Date 09/21/2023
Application Deadline
Open Until Filled Yes
Position Type Postdoctoral Scholar
Position Title Post-Doc Research Associate
Vacancy ID PDS003973
Full-time/Part-time Full-Time Temporary
Hours per week 40
FTE 1
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range
Proposed Start Date 10/09/2023
Estimated Duration of Appointment 12 Months

Position Information


Primary Purpose of Organizational Unit
The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.
OUR VISION
Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding.
OUR MISSION
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research.
Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.
Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.
Position Summary
A position for a Postdoctoral Research Associate (RA) in the laboratory of Dr. Nicholas Brown in the Department of Pharmacology, University of North Carolina, School of Medicine. Join our team investigating the mechanistic underpinnings of protein ubiquitination. This process is involved in nearly every eukaryotic signaling pathway and is governed by ubiquitin ligases. These enzymes are disrupted in countless disease processes, including Alzheimer’s disease. Using innovative approaches, such as Time-Resolved Cryo-EM, we explore how ubiquitin ligases recruit substrates and build a proteasome degradation signal (e.g., Bodrug et al., NSMB, in press; Welsh*, Bolhuis* et al., EMBO J 2022; Martinez-Chacin et al., NSMB 2020). These principles are used to understand targeted protein degradation, an emerging method to eliminate unwanted proteins for therapeutic purposes.
Minimum Education and Experience Requirements
A Ph.D. and/or M.D. in biomedical or related sciences is required.
Required Qualifications, Competencies, and Experience
Candidates are expected to have strong problem solving, oral, and written communication skills, excellent interpersonal skills and the ability to work effectively and collegially with colleagues in a laboratory setting, as well as independently. Prior experience in protein biochemistry and
Preferred Qualifications, Competencies, and Experience
Prior experience in protein biochemistry and structural biology approaches is preferred; however, we provide a valuable opportunity for those interested in learning these techniques to advance their careers.
Special Physical/Mental Requirements
Special Instructions
For information on UNC Postdoctoral Benefits and Services click here
Quick Link https://unc.peopleadmin.com/postings/265940

Posting Contact Information


Department Contact Name and Title Maria Montemurro, HR Consultant
Department Contact Telephone or Email maria_montemurro@med.unc.edu
Postdoctoral Affairs Contact Information

If you experience any problems accessing the system or have questions about the application process, please contact the University’s Equal Employment Opportunity office at (919) 966-3576 or send an email to equalopportunity@unc.edu.

Please note: The Equal Employment Opportunity office will not be able to provide specific updates regarding position or application status.

Equal Opportunity Employer Statement

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.


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