The Kurie Laboratory in the Department of Thoracic/Head and Neck Medical Oncology, MD Anderson Cancer Center, seeks to ll multiple postdoctoral positions. Our research focuses on the molecular mechanisms by which lung cancer cells generate a pro-metastatic tumor microenvironment, with three complementary areas of investigation: (1) a tumor cell-derived collagen modifying enzyme called lysyl hydroxylase 2 (LH2) that functions as a nodal regulator of brosis and immunosuppression; (2) Golgi-directed secretory processes driven by oncogene-induced transcriptional programs; and (3) epithelial-to-mesenchymal transition as a driver of brosis and immunosuppression in the tumor microenvironment.

LEARNING OBJECTIVES
Postdoctoral fellows will benet from training in model development and characterization, including 2- and 3-dimensional cell culture models and autochthonous and orthotopic mouse models that recapitulate features of the TME in human cancers and translate those ndings to clinical and molecularly annotated human tumor tissue banks. Fellows will have educational and mentoring opportunities (e.g., pilot funding, grant-writing courses, and teaching and mentoring experience in our summer undergraduate and graduate internship programs) and extensive opportunities to gain presentation skills at weekly Kurie lab meetings, monthly departmental joint lab meetings, monthly meetings for our programmatic research groups (NCI-funded SPORE, CPRIT-funded MIRA), and annual conferences (e.g., Keystone, Gordon, Cold Spring Harbor, AACR).

ELIGIBILITY REQUIREMENTS
Individuals who have completed a Ph.D. and have training relevant to the position. Qualied individuals will demonstrate the potential for research as evidenced by their peer-reviewed publications and funding. Background in cancer biology and expertise in the design and execution of cell culture and in vivo experiments that incorporate a variety of molecular and cellular techniques is desirable.

POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the "Kirchstein - NRSA". This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:
- Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid Education Vacation and Sick Leave
- Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
- Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illness-related reduced salary pay program
- Health Savings Account and Dependent Care Reimbursement flexible spending accounts
- Fertility benefits
- State of Texas longevity pay
- Extensive wellness, fitness, employee health programs and employee resource groups