The Balachandran laboratory seeks Postdoctoral Associates to pursue exciting projects centered on the mechanism and role of programmed cell death during viral infections, and in exploiting these findings for the treatment of infectious, inflammatory, and malignant disease. Specifically, the lab has identified pathways of ZBP1/RIPK3-driven necroptosis triggered in influenza virus-infected cells, and now looks to explore how these pathways are activated, in which cell types they operate, and how they contribute to immune responses, as well as to pathogenicity, in various disease settings. Potential projects will utilize proteomic, CRISPR-based screening, and cell biological approaches to identify new nodes in these pathways, to determine their significance to antiviral immune responses, and to leverage them for the treatment of human disease. Please see Zhang et al. Cell , 2020 (PMID: 32200799) and Zhang et al. Nature, 2022 (PMID: 35614224) for examples of the research carried out in the laboratory. The ideal candidate will hold a Ph.D., with training in host-pathogen interactions, endogenous retroviral elements, innate immunology and/or cancer immunology. Familiarity with techniques in cell biological and signal transduction research will be essential, and prior experience with cell culture and in vivo mouse models of virus pathogenesis and/or tumor immunology will be an advantage.  Please email CV, a cover letter briefly outlining research interests, and names of three references to Siddharth.balachandran@fccc.edu .