Ophthalmology

Full Time

72983BR

Job Summary

The Ullian Lab (http://vision.ucsf.edu/ullian) at University of California San Francisco is seeking a Research Associate for a cell and molecular biology laboratory with a focus on neuroscience.

Under direct supervision and training, the research associate (SRA I/II) will be responsible for maintenance, differentiation, and profiling of human pluripotent stem cell-derived astrocytes, neurons, and microglia to discover molecular mechanisms impacting neurodegeneration. In addition, functional analysis of the derived cells will be conducted by measuring maturation markers and using targeted assays. Also, be in charge of assembling the differentiated neurons, astrocytes, and microglia in 3D structures following a protocol developed by the Ullian lab.

We will be using patient-derived cell lines to model neurodegenerative disorders with a focus on amyotrophic lateral sclerosis and frontotemporal dementia. The successful candidate will assist laboratory research by providing technical assistance, preparing and arranging reagents, ordering and inventory of stocks, and maintaining an extensive research database for cell banking. They must be willing to work in a research team, be organized, enjoy problem-solving, and have strong communication skills.

Techniques may include, but are not limited to: basic molecular biology, biochemistry, cell culturing, genome editing, cloning, immunofluorescence, immunohistochemistry, and microscopy. The Research Associate will work under the direct supervision of a postdoctoral fellow and/or a higher-level SRA. There may be opportunities for co-authorship of manuscripts if the incumbent is motivated and exerts extra effort.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up):TCS Non-Academic Titles Search (ucop.edu)

Please note: The compensation ranges listed online for roles not covered by a bargaining unit agreement are very wide, however a job offer will typically fall in the range of 80% - 120% of the established mid-point. An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The UCSF Department of Ophthalmology is one of the leading ophthalmology departments in clinical care, training, and research nationwide. The Department of Ophthalmology is one of the largest recipients of federal grant funds among peer departments. We are ranked 1st in National Eye Institute Funding and 2nd in overall National Institutes of Health (NIH) funding in the country.

Additionally, we have been the #1 recipient of the Research to Prevent Blindness funding nationwide with nearly $1.2 million granted in a single year. Overall, the Department has a wide-ranging portfolio of 60 active research grants. UCSF’s renowned eye care services have a new state-of-the-art home.

In November 2020, the Wayne and Gladys Valley Center for Vision opened its doors. Located at UCSF's Mission Bay Campus, the center houses the Vision Clinics, where many of UCSF's eye care programs relocated, as well as research and teaching facilities.

Ophthalmology conducts its patient care, teaching, research, and public service activities currently at multiple UCSF campuses: Parnassus, Mt. Zion, Veteran’s Administration Medical Center (VAMC), San Francisco General (SFG), East Bay and Benioff Children’s Hospital at Mission Bay and in Oakland. The department sponsors numerous invited speakers, research seminars, journal clubs, as well as a postdoctoral training program focused on mentorship, networking, and recognition.

The UCSF Department of Ophthalmology consists of approximately 300 FTE’s (including UCSF Health employees) including faculty, basic scientists, postdoctoral scholars, graduate students, residents, fellows, clinical, research, and administrative staff.

Required Qualifications

SRA I:

• BA/BS/BSc Degree in Molecular and Cell Biology, Neuroscience, or related biological science and knowledge of, or experience with, the basic techniques or methods required by the position; and/or equivalent experience/training
• Cell and molecular biology experience as obtained in school
• Knowledge of basic molecular biology techniques acquired in school
• Knowledge of basic biochemistry techniques acquired in school
• Strong communication skills, computer skills, be highly motivated and work well as a team or independently
• Efficient and organized with meticulous record-keeping skills
• Ability to work independently and effectively after receiving instruction, while managing and prioritizing multiple projects

• In addition to the above, one year of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position; and/or equivalent experience/training

Preferred Qualifications

• Laboratory experience with human pluripotent stem cell
• Experience generating human iPSC derived astrocytes and neurons
• Experience generating viruses
• Experience with CRISPR and genome engineering
• Computational skills for RNA-seq data analysis

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Job Code and Payroll Title

009613 SRA 1

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Location

Parnassus Heights (SF)

Additional Shift Details

M-F; 8am-5pm