Postdoctoral Research Associate - Neurosurgery

Job Description

Position Summary

Tumor and Immunometabolism and Functional Epigenetics

Postdoctoral positions are available in the laboratory of Alexander Stegh at The Brain Tumor Center, Washington University School of Medicine. Our laboratory aims to understand the metabolic adaption of Glioblastoma, in particular focused on the intersection between metabolic and epigenetic regulation. Candidates with broad backgrounds in tumor biology, immunology (immuno-)metabolism, molecular biology and genetics are all welcome to apply.

Our laboratory uses metabolomics, flux studies, single cell and other omic approaches to discover key metabolic pathways that contribute to Glioblastoma progression and develop innovative pharmacological strategies to therapeutically target those pathways (Cell Reports 2017, Science Adv 2019a, 2019b). Ongoing projects in our lab include:

• Identifying modes of epigenetic regulation in response to wild-type isocitrate dehydrogenase expression in tumors and tumor-associated immune cells.
• Unveiling new fundamental roles of regulated cell death programs, such as ferroptosis, in Glioblastoma progression and therapy susceptibility.
• T and myeloid cell metabolism.
• Small molecule preclinical development.

Information on being a postdoc at Washington University in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ .

Required Qualifications

Candidates must hold a Ph.D and/or M.D. degree (or anticipate receiving their degree in the near future).

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

Interested candidates should send a cover letter, their C.V. and a list of 2 or 3 references to: stegh@wustl.edu .

Accommodation

If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.