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Postdoctoral Scientist - Dr. Casero Lab - Bioinformatics
Cedars Sinai Medical Center in Los Angeles, California
Date Posted 10/08/2020
Admin-Laboratory and Research
Employment Type
Application Deadline Open until filled

Requisition # HRC0363657Apply Now

Principal Investigator, David Casero, PhD is looking for a Postdoctoral Scientist to join the team!

The Inflammatory Bowel and Immunobiology Research Institute (IBIRI) is a multidisciplinary basic, translational and clinical research program devoted to discovering the causes of Inflammatory Bowel Disease (IBD) with the goal of improved treatment approaches and prevention. The laboratory of Dr. David Casero is looking for highly motivated computational scientists who are passionate about diving into complex biological data!

The group of Dr. David Casero applies Bioinformatics, Computational Biology and high-throughput sequencing data to analyze gene regulatory pathways in stem cell and immunobiology. We are particularly interested in understanding the establishment and maintenance of normal tissue homeostasis, supported by molecular interactions between members of the tissue microenvironment (e.g., epithelial, mesenchymal, and immune cells) and environmental factors (e.g., signals modulated by the microbiome). With the help of our collaborators, our lab aims to harness the power of multi-omics libraries to generate the novel data-driven hypothesis that can pave the way into future mechanistic and translational studies.

For more information about Dr. Casero’s research please visit: https://www.cedars-sinai.org/research/labs/casero-lab.html

Are you ready to be a part of ground breaking research?

Our goal is to build a dynamic team dedicated to analyze and interpret multi-omics sequencing datasets in both basic and translational studies. You will join a highly collaborative, interdisciplinary, and cutting-edge environment, and we work together with a team of computational, wet-lab, and physician-scientists. Our collaborative network aims to develop a knowledge-based, integrative effort to better understand the aberrant regulatory networks that underlying IBD pathogenesis and future therapeutic approaches. We have a number of ongoing projects – cross-talk between different cell types advancing tissue homeostasis and regeneration, discovery and single-cell characterization of novel non-coding RNAs, and the integration of non-coding RNA expression signatures into genetic association analyses – that provide an outstanding opportunity for highly multidisciplinary research in a relevant biomedical problem within in collaboration with world-renowned IBD scientists.

Additional Duties and Responsibilities:

  • Analyze and integrate multi-omic (transcriptomics, epigenomics, metagenomics) sequencing datasets into quantitative models
  • Interact continuously with our bench collaborators to guide and propose new experiments and use data to its full potential
  • Conduct projects independently, maintains records and databases, and facilitate data access to wet-lab collaborators
  • Provide mentorship and supervise the work of graduate students and provide expert opinion and guidance on data analysis and experimental design.
  • Participate and present research outputs in group meetings, collaborative meetings, project retreats and seminars. Present at national and international conferences
  • Perform routine and complex laboratory procedures throughout the training period
  • Assist in the preparation of grant proposals, not responsible for generating grant funds
  • May participate in publications and presentations as author or co-author

Educational Requirements:

Doctorate (PhD) in area directly related to field of research specialization (systems biology, computational biology, bioinformatics, applied mathematics, theoretical physics, computer science)

Experience we are seeking:

  • Independently works on research projects designed by a mentor (typically the PI) within an area of specialization. Acquires thorough technical and theoretical knowledge of research projects and objectives during one to five (1-5) year post-doctoral appointment
  • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis and operation and maintenance of specialized equipment.
  • Knowledge of safety standards and maintenance of specialized equipment.
  • Experience in genomics and high throughput data analysis
  • Significant experience in Python, R, matlab or other major programming languages
  • Strong mathematical background and analytical skills

  • Working Title: Postdoctoral Scientist - Dr. Casero Lab - Bioinformatics
  • Department: Home Dept - Gastroenterology
  • Business Entity: Academic / Research
  • City: Los Angeles
  • Job Category: Academic/Research
  • Job Specialty: Postdoctoral
  • Position Type: Full-time
  • Shift Length: 8 hour shift
  • Shift Type: Day
Apply Now

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu). For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through March each year) as a condition of employment, and annually thereafter as a condition of continued employment.

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