Posted: 20-Oct-23

Location: Ann Arbor, Michigan

Salary: Open

Categories:

Internal Number: 240991

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

We are seeking a Postdoctoral Scientist to work within the group of Dr. Jay Brito Querido in the Department of Biological Chemistry at the University of Michigan Medical School.

The lab is using cryo-electron microscopy and biochemical approaches to study the role of a conserved family of enzymes called DEAD-box (DDX) RNA helicases in the regulation of mRNA translation in humans. The goal is to understand the mechanism underlying translational regulation by these RNA helicases, which should provide insights into processes controlled by translational regulation, including brain development.

The primary responsibility is to conduct research to advance the understanding of the role of RNA helicases in the regulation of mRNA translation. The successful candidate will develop and apply different techniques, including single-particle cryo-electron microscopy, to study translational regulation. This position will have access to state-of-the-art facilities at the Life Sciences Institute and in the Department of Biological Chemistry.
 
In addition, this position will contribute to laboratory seminars and discussions, allowing the candidate to impact the direction of their research project and other projects within the research group. Assist in training lab members. Contribute to preparing research for publication and ensure that the research is performed according to best practices – in compliance with the University of Michigan and funding agency's guidelines. 

PhD in biological sciences or related field with at least 2-3 years of laboratory research experience. The ability to work productively in a team environment with people from diverse backgrounds, work with limited supervision to identify a broad range of techniques to achieve the project's primary goal. The successful candidate will be highly motivated, able to multi-task efficiently, work independently and be committed to research. Some evening and weekend work may be required.

Experience in RNA biology, helicases, structural biology, and neurology is an advantage.  

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal opportunity/affirmative action employer.

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About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.
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