Department of Molecular and Cellular Biology at Baylor College of Medicine (BCM) is seeking a Junior Faculty position at the level of Instructor. BCM is located within the Texas Medical Center in Houston, a premier research and clinical environment.

The primary responsibility is to serve as Technical Director of the Advanced Cell Engineering and 3D Models Core (ACE-3D), an Institutional Advanced Technology Core (ATC) facility at Baylor College of Medicine. This involves management of the day-to-day operations of the core including supervision of research staff, scientific oversight of core supported projects, budgets, quality control and reporting of results to investigators.

Technical Core Director duties are to manage the day-to-day operations of the core . This includes consultation with core users on design of projects, supervision of research staff, scheduling projects, overseeing and troubleshooting projects, communicating, and reporting results to core users and assuring quality control.  Other administrative duties include managing budgets and invoicing core users through the iLabs system, ordering supplies, equipment maintenance, preparing annual progress reports and participating in the Advanced Technology Core Directors standing committee for strategic planning.  In addition to management duties, the Technical Core Director is expected to contribute to hands-on lab bench experiments supporting core projects and development of novel technologies and methods.  As a junior faculty, the Technical Core Director is also expected to participate in submission of grants for direct support of core operations, to present research seminars, conduct workshop tutorials on core technologies and participate in training and teaching opportunities.

The primary mission of the ACE-3D Core is to provide technical and scientific expertise for functional genomics in  cell-based model systems including advanced 3D organoid cultures.  The core provides large-scale whole genome loss and gain of function screening projects using conventional shRNA/siRNA and CRISPR/Cas9-based genome editing services.   Another major focus of the core is the use of CRISPR technology for generating custom gene knockout, point mutation knock-in, and large fragment insertion/deletion mutations in a variety of cell lines as disease models.  These functional genomic projects require advice and guidance at every stage, from guide design, selecting the best model cell lines, to cloning and verification of gene knockout and knock-in cell lines.  The core lab provides these services to over 35 BCM investigators per year and has significant impact on research productivity and mission of the Institution. Because this is a research core facility conducting projects for many investigators, the position requires excellent communication (written and oral), organizational, record keeping and customer service skills. 

• Post terminal degree education (e.g., residency, postdoctoral training/fellowships).

• Ph.D. in biological sciences with emphasis in biochemistry, molecular biology, cell biology, and functional genomics.  At least 2 years of post-doctoral research training in an academic institution in relevant areas and at least 5 years of academic research experience in CRISPR-based genomic editing and practical experience with laboratory management responsibilities. 

Diversity among Baylor's students, trainees, faculty, and staff is a prerequisite to accomplishing Baylor's institutional mission, and to maintaining the highest standards in training for healthcare providers and biomedical scientists, scientific innovation, and patient-centered care. Baylor is committed to ensuring equal opportunity for all qualified persons without considering race, color, national origin, creed, sex, sexual orientation, ancestry, age, veteran status, or disability unrelated to job requirements.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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