1 Purpose...... to reimagine medicine. Join the Novartis Institutes for Biomedical Research (NIBR) as a Discovery Postdoctoral Fellow and contribute to unraveling one of the most important biological pathways contributing to hypertension, heart failure (HF), renal dysfunction and metabolic disease - the natriuretic peptide pathway.

NIBR is the innovation engine of Novartis. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.

Our Heart Failure discovery team within the department of Cardiovascular and Metabolic Diseases, in Cambridge, MA is seeking a highly motivated and team-oriented Postdoctoral Fellow to join our NPR1 program. The NPR1 signaling pathway is a fundamental contributor to hypertension and heart failure pathobiology, and drug candidates for this pathway are in clinical trials. NPR1 biology also is implicated in related indications that exacerbate HF, including chronic kidney disease, pulmonary arterial hypertension, and metabolic disease. As a Discovery Fellow, you will focus on deepening our fundamental understanding of NPR1 in one or more disease settings and carry out translational research to determine additional key indications of high unmet medical need. Multiple genetically engineered mouse models, surgical models and pharmacological tools are already available within the department. In addition, you will have access to experts across subject areas and platforms within NIBR, as well as academic experts in the field, and you will be encouraged to forge collaborations with these scientists. This is an outstanding opportunity to drive innovative, interdisciplinary research expected to be published in leading journals.

NIBR Fellows join our vibrant postdoctoral community for dedicated events, including the monthly postdoctoral seminars and our annual Research Day Symposium. All NIBR Fellows participate in our robust curriculum designed to develop scientific and professional skills. The postdoctoral term is for up to 4 years.

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What You'll Bring to the Role:

* PhD in a relevant field such as Cardiovascular Physiology, Vascular Biology. Pharmacology, Molecular Biology, Biochemistry, Biophysics, or related field (PhD students in the last year of their thesis work are eligible to apply)
* A solid understanding of receptor-dependent signaling and second messenger systems.
* Experience with primary cell culture and/or animal models of HF, renal disease, pulmonary hypertension and/or metabolic disease a benefit.
* Demonstrated ability to work independently, and collaboratively with interdisciplinary research teams.
* Strong publication record or other scientific achievements (i.e. awards, patents)
* Excellent communication skills, both written and oral
* Passion for fundamental exploratory research and boundless curiosity

How to apply:

Please submit your CV and cover letter by June 30 for consideration.

For more information about our postdoctoral program, please visit: https://www.novartis.com/careers/postdoc-program

Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives, and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here: https://www.novartis.com/about/strategy/people-and-culture

You’ll Receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity and Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

The pay rate for this position at commencement of employment is expected to be $75,000 per year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

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