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Work type:Research Faculty
Senior management: College of Science
Department: Chemistry
Location:Blacksburg, Virginia
Categories:Research / Scientific

Job Description

The Senior Research Scientist position will involve structure-activity profiling of lipid-like heterocycles to inhibit the sphingosine-1-phosphate transporter Spns2 as well as mitochondrial uncouplers. Through an iterative process of synthesis and biological evaluation both in vitro and in vivo, drug-like compounds with once-a-day oral dosing are expected to be developed. The ideal candidate is expected to have (i) a Ph.D. in Chemistry, (ii) a record of publications, (iii) the ability to work independently with high self-motivation, and (iv) strong communication skills.

Responsibilities will include:
- Help faculty supervisor write grants
- Prepare regular written progress reports and present oral reports.
- Work with faculty supervisor and graduate students.
- Find solutions to scientific problems that arise in the research.
- Pursue research goals with limited consultation and little supervision.
- Supervise/train postdocs, undergraduate, and graduate students in laboratory procedures.
- Develop project research strategies, execution, and interpretation of research projects to gain
practical experience in the field.
- Prepare and present professional talks, reports, and publications.
- Engage in collaborative work with peers to achieve research objectives.
- Actively promote a culture of safety

Required Qualifications

Required Qualifications:
- Doctoral degree in chemistry or closely related field(s) with significant (4 years) postdoctoral or comparable experience.
- Competent ability as a synthetic chemist with experience with methodology development as well as medicinal chemistry.
- Well skilled with purification and characterization of organic compounds, the latter using nuclear magnetic resonance, IR, mass spec, and chromatographic (HPLC/column chromatography) techniques.
- Ability to independently develop synthetic schemes and analyze data.
- Ability to define, organize, and carry out work with minimal supervision.
- Strong work habits and the ability to work independently as well as with a research group.
- Strong communication skills.

Preferred Qualifications

Preferred Qualifications:
- Knowledge in pharmacology parameters such as absorption, distribution, metabolism and excretion.
- Evidence of developing publications based on research.
- Creativity, independence, and high motivation.
- Ability to establish and maintain effective working relationships with all levels of personnel in the organization.

Appointment Type

Restricted

Salary Information

Commensurate with experience 

Additional Information

The successful candidate will be required to have a criminal conviction check.

About Virginia Tech

Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges , a school of medicine , a veterinary medicine college, Graduate School , and Honors College . The university has a significant presence across Virginia, including the Innovation Campus in Northern Virginia; the Health Sciences and Technology Campus in Roanoke; sites in Newport News and Richmond; and numerous Extension offices and research centers . A leading global research institution, Virginia Tech conducts more than $500 million in research annually.

Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law.

If you are an individual with a disability and desire an accommodation, please contact Leslie Cherry-Marshall at lmcherry@vt.edu during regular business hours at least 10 business days prior to the event.