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Systems Neurodevelopment

Job Description


A fully funded postdoctoral position is available in the laboratory of Dr. David Leopold to apply cutting edge methods to study the development of brain circuits related to visual cognition. Research in the Leopold laboratory combines emerging technologies, such as broad viral transduction of the fetal brain, with state-of-the-art tools such as fMRI and electrophysiology, to
investigate the maturation of cortical circuits in rodent and primate models. Of particular interest is the gradual development and specialization of cortical circuits supporting high-level visual perception. This includes visual circuits tailored for complex social interactions, which are known to be affected in human psychiatric disorders.

Central to our research is the precept that in order to understand the systems-level organization of the brain, it is essential to consider its developmental and evolutionary history, as well as the natural conditions under which the brain operates. The immediate goal of the research program is to identify the sequence of events governing how functionally defined cortical circuits become established during the first months of life, and how this maturation is affected by visual experience. Our recent progress in prenatal genetic modification of the brain has opened new doors to addressing such questions. Research in the laboratory is supported by a rich NIH network of core facilities that offer services in animal brain imaging (MRI/PET/CT), transcriptomics, microscopy, genetic engineering, behavioral and cognitive testing, veterinary and breeding expertise, data analysis, high-performance computing, and other areas.


Qualifications:

Interested candidates must be completing or should have obtained a Ph.D. or M.D. degree with background in Systems or Molecular Neuroscience, Developmental Biology, Neuroanatomy, Cell Biology, Genetics, Physiology, Bioinformatics, Computational Biology or a related discipline and have fewer than 5 years postdoctoral experience. Experience in animal models of neurodevelopment, bioinformatics, and animal cognition is highly desirable but not required. In general, quality of past research is more important than experience in a specific field.

The successful applicant will be fully supported by NIH intramural funds and offered competitive stipend/health insurance commensurate with experience and accomplishments.


To Apply:

Candidates from underrepresented backgrounds in health-related sciences, persons with disabilities or other circumstances are encouraged to apply. Interested individuals should send their CV, a brief description of their background, interests and career goals, and the names of three people who can be contacted for reference letters to Dr. David Leopold (leopoldd@mail.nih.gov ).

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.


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