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Immunology Research Specialist- Garcia Lab

HHMI

Job Description



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HHMI is focused on supporting and moving science forward in a variety of different ways ranging from conducting basic biomedical research, empowering educators, inspiring students, developing the next generation of scientists – even stretching into film and media production.  Our Headquarters is in the greater Washington, DC metro area and is home to over 300 employees with expertise in investments, communications, digital production, biomedical sciences, and everything in between.  The work housed here supports and augments the groundbreaking research conducted in HHMI labs across the nation.  As HHMI scientists continue to push boundaries in laboratories and classrooms, you can be sure that your contributions while working here are making a difference.

We are seeking an Immunology Research Specialist to support the lab of Dr. Christopher Garcia at Stanford University. We are looking for an immunologist with skills in T cell biology, T cell assays (and other immune cell types), immune signaling and profiling, and mouse tumor models. The Garcia lab is interested in the biochemistry and cell biology of cell surface receptors and their ligands. Using a range of methodologies, the Garcia lab investigates how ligand recognition and signaling coordinate with the physiology of the cell. In addition to understanding basic aspects of receptor signaling (second messengers, gene expression) and structural biology, the team is also interested in the creation/engineering of novel receptor ligands using protein engineering. A major aim of their work is to synthetically leverage natural biological signaling mechanisms as a path to potential therapeutics. More information about this lab can be found on his website https://med.stanford.edu/garcialab.html

The candidate will have expertise in the general area of immunology, with preferred experience in analyzing immune cell signaling and profiling (T cell, B cell, NK cell, macrophage), cell functional assays, gene expression both in vitro, ex vivo and in vivo. Prefer some familiarity with recombinant protein expression from mammalian cells (i.e. 293).  Prefer experience in immunology, both in vitro and in vivo, with experience in analyzing TCR and cytokine signaling pathways, cell biology and gene expression, as well as familiarity with standard in vivo tumor models in mice. The successful candidate will contribute to ongoing projects in the lab aimed at developing new immunotherapeutic molecules and strategies. The position requires a highly self-motivated, accomplished individual with an outstanding track-record of innovation and success in both graduate school and postdoctoral research with a strong publication record. The position will require working in team environments supporting lab projects in a collaborative fashion, as well as individual projects. It is expected that the individual will contribute to publications, as well as assisting in basic aspects of grant preparation and progress reports.

What you’ll do

  • Perform various specialized scientific investigative procedures in support of assigned research projects.

  • Conduct literature reviews to be used in determining most suitable research methods.

  • Identify methodological problems in research protocol and assist in implementing modifications to optimize experimental results.

  • Coordinate specialized and novel research functions.

  • Train others in complex technical protocols.

  • Prepare and present written or oral progress reports concerning studies, including assembly, organizational and interpretation of data.

  • Use software applications to assemble, manipulate, format and/or perform statistical analyses of standard data.

  • May configure, operate, and/or maintain specialized equipment.

  • May develop, or lead the development of, training tools.

  • May plan for and provide working supervision to a group of laboratory employees of lower grade engaged in the performance of technical and professional work and a variety of complex to routine to complex tasks.

  • Assisting the PI with research related administrative tasks such as grant writing, grant progress reports, publications, monitoring materials transfer and collaboration agreements, interfacing with biotech companies to lead collaborations.

  • Working with students, trainees at all levels to indoctrinate them into the lab.

Skills You Bring:

  • A Ph.D. or M.D. degree with at least 3 years of relevant postdoctoral research experience in academia and/or industry is required.

  • A strong background in immunology, in vitro and in vivo analysis of TCR and cytokine signaling, in vivo mouse tumor models, and preferably some experience with protein biochemistry, phospho-flow.

  • The successful candidate must be technically rigorous, possess exceptional organizational skills and attention to detail and have a track-record of excellence, innovation and productivity in research.

  • Excellent interpersonal, communication and writing skills are imperative.

  • The successful candidate must be able to work both independently and collaboratively and will have additional roles in the training of postdoctoral fellows, graduate students and staff members.

  • Ability to prepare research reports for presentation to a large audience.

  • Ability to draft research manuscripts. 

  • In-depth knowledge of multiple scientific areas and of the underlying principles and concepts. 

  • Able to critically review information. Readily understands new concepts.

  • Ability to develop innovative processes to achieve goals. Reviews work activities to determine where new information could improve processes or move projects forward.

Compensation Range

$67,390.00 (minimum) - $84,200.00 (midpoint) - $109,480.00 (maximum)

Pay Type:

Annual

HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate's education, previous experiences, knowledge, skills and abilities, as well as internal equity when making job offers. Typically, a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.


Physical Requirements

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances or other hazardous materials.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.


Compensation and Benefits

Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. 

HHMI is an Equal Opportunity Employer


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