Job Summary:

A postdoctoral position is immediately available in the joint laboratory of Dr. Shaikh Atif and Dr. Michael Falta in the Division of Allergy and Clinical Immunology in the Department of Medicine at the University of Colorado Anschutz Medical Campus. The Department of Medicine provides an excellent research environment and state of the art research facilities.  The Atif-Falta laboratory is looking for a talented postdoctoral fellow to work on projects exploring the innate and adaptive cellular and molecular pathways involved in the immunopathology of pulmonary diseases including sarcoidosis and chronic beryllium disease. Research will include working with humanized transgenic murine models of disease and may utilize human blood and bronchoalveolar lavage samples. In the past several years, findings from the lab have been published in the Journal of Experimental Medicine, Journal of Clinical Investigation, JCI Insight, and European Respiratory Journal.

Key Responsibilities:

We are seeking an enthusiastic individual to join our research team which is involved in examining the role of innate and adaptive immune cells in sarcoidosis and chronic beryllium disease. The successful candidate will:

• exploit cutting-edge technologies including multi-omics approaches (e.g., RNA-seq, single-cell seq, and CITE-seq), multicolor flow cytometry and fluorescence imaging in addressing scientific questions that require a combination of basic science and clinical translational research skills.
• work in a multidisciplinary research environment to develop pipelines for analyzing large transcriptomic and T cell receptor sequencing data and lung image data.
• work with mouse models of human disease that involve breeding, genotyping, treatment (intravenous, intranasal, intratracheal), harvesting, and processing of organs.
• perform assays to assess the adaptive immune responses in mouse disease models. These include ELISPOT, ELISA and T cell proliferation assays.
• have the opportunity to participate in other ongoing research projects including antigen discovery studies. This includes identifying candidate disease-relevant T cell receptors, constructing T cell hybridomas using standard molecular biology techniques, and working with synthetic positional scanning peptide libraries, peptide mixtures and peptide deconvolution strategies to identify stimulatory T cell mimotopes and epitopes.
• be responsible for the timely completion of projects and accurate recording of work in lab notebooks and computer databases.
• participate and present data in weekly lab meetings and periodic meetings with the PIs to discuss research progress and career goals.
• be involved in the maintenance and cleaning of lab workspaces including proper care of instrumentation.
• build a thorough knowledge of scientific developments in the field by reading scientific articles and participating in conferences.
• contribute to writing and editing scientific manuscripts as a first or co-author.
• apply for postdoctoral fellowships, training grants and other supplemental funding in support of their independent projects with the consent of PIs.
• This position offers the opportunity to apply for postdoctoral fellowships, training grants and other supplemental funding in support of their independent projects with the consent of PIs.

Why Join Us:

The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, and holidays and more. To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness .

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

• Education: Ph.D. in the biological sciences, or M.D., with hands-on research experience.
• Experience in animal handling
• Special Skills:  Handling of human blood and BAL samples and murine tissues including lungs and spleen is required.

Preferred Qualifications:

• Ph.D. in a related discipline, M.D., or equivalent required. Prior experience of analyzing large single-cell RNA seq data sets

Knowledge, Skills and Abilities:

To be successful in this position, candidates will need the following:

• Excellent verbal and writing skills.

How to Apply:

For full consideration, please submit the following document(s):

Applications are accepted electronically ONLY at www.cu.edu/cu-careers .

Questions should be directed to: Marc Steinman, marc.steinman@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until position is filled.

Anticipated Pay Range:

The starting salary range (or hiring range ) for this position has been established as HIRING RANGE:

The salary range (or hiring range) for this position has been established at $54,840 - $59,784

The above salary range (or hiring range ) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu ?.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date.  Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Unit-Specific Exemptions:

• Anschutz Campus – Accommodations may be granted for medical or religious reasons.

The University of Colorado seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.