Job Description

A postdoctoral/immunologist position is available in the laboratory of Dr. Igor Koralnik, Chief of the Neuro-Infectious Diseases and Global Neurology Division at Northwestern University Feinberg School of Medicine, in the Department of Neurology.

By working closely with multifaceted teams of the Neurology department and international collaborators, the successful candidate will be well placed to undertake cutting-edge research aimed at elucidating the immune response against SARS-CoV-2 in long COVID patients with neurologic symptoms. These include brain fog, fatigue, and sleep disturbances after COVID-19. By understanding how SARS-CoV-2 infection alters the balance between antiviral and autoimmune T cell responses in patients with long COVID, we hope that novel treatment and prevention options will be uncovered.

Using blood samples, cell culture techniques, and immunoassays, the successful candidate will be expected to take a leading role in developing and executing internationally recognized research projects aimed at:

• determining how SARS-CoV-2 reprograms the T cell response to impact neurologic function in long COVID
• assessing how the balance between antiviral and autoimmune T cell responses contribute to long Neuro-COVID symptoms
• investigating how T regulatory cell function correlates with sleep disturbances in elderly patients with and without long COVID
• correlating results from immunoassays, proteomics, and T Cell Receptor sequencing data with clinical symptoms of long COVID

We are looking for an enthusiastic and talented postdoc with training in T cell immunology to join our team. Applicants would preferably have a PhD or MD/PhD within immunology with a focus on virology/microbiology or autoimmunity. Applicants must have already graduated or anticipate graduating within the next 3 months. A strong record of peer-reviewed publications, including first authorship will be a plus, but is not a requirement.

Candidates must have expertise in at least two of these areas:

• Familiarity with immunological techniques, including but not limited to: ELISA, ELISPOT, cytotoxicity assays.
• Experience with flow cytometry, including using FlowJo for data analysis.
• Extensive experience with cell culture techniques, including generating and maintaining T cell lines.
• Experience with analysis and data visualization of transcriptomic data.

Other desirable attributes include:

• Experience in/working knowledge of biostatistics/statistical viromics or genetics

Interested applicants should email a CV, a brief description of research interests and contact details for three references to Igor.Koralnik (at) northwestern.edu

Job Type: Full-time

Schedule:

• 8 hour shift

Work Location: One location

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